DOUGH: Sprinkle yeast over warm water. Add teaspoon of sugar and stir to combine. Let sit for 5-7 minutes to allow mixture to bubble and activate.
In the bowl of a stand mixer, whisk together yeast mixture, brown sugar, eggs, and pumpkin puree. Add 2 cups of flour, salt, cinnamon, and turmeric to mixing bowl. Use the dough hook attachment to mix together. Add another cup of flour. Continue to knead on low speed until adding softened butter one tablespoon at a time. Add remaining flour and knead until dough is smooth and cleans the sides of the bowl.
Transfer dough to a lightly greased bowl. Cover with plastic wrap and let sit at room temperature for about an hour until dough has doubled in volume.
CARAMEL: In a medium sauce pot, combine cream and brown sugar. Stir to combine. Set over medium heat and bring to a boil. Once boiled, let simmer for 3-5 minutes. Remove from heat and add pinch of salt. Stir and let cool. Store in fridge until ready to use. Reheat as necessary.
FILLING: In a small bowl, mix together softened butter and pumpkin puree. In another small bowl, whisk together sugar, brown sugar, and pumpkin pie spice mix. Set aside until ready to assemble.
ASSEMBLY: Lightly grease a 9 x 12 inch baking dish. Sprinkle pumpkin seeds and sliced almonds over bottom of dish. Pour cooled caramel sauce into baking dish over seeds and nuts.
Punch dough risen dough. Transfer to a clean working surface. Roll dough into a 20 x 14-inch rectangle. Spread butter mixture over dough. Sprinkle spiced sugar mixture on top.
Starting at the long side, roll dough into a log. Slice log into 12 equal parts. Place rolls baking dish. Cover with plastic wrap and let rest for 30-45 minutes at room temperature to allow rolls to rise.
Preheat oven to 350 degrees F. Remove plastic wrap and bake rolls for 30-35 minutes until golden brown on top and the internal temperature of the rolls reach 185 degrees F. Let the rolls sit in the baking dish for 5 minutes before inverting into a serving dish. Serve warm with additional caramel sauce, if desired.